Home

Orthotopic and heterotopic transplantation

Orthotopic and heterotopic tracheal transplantation model

Conclusions: Orthotopic tracheal transplantation in mice can be considered as a model to study early stages of obliterative bronchiolitis, and heterotopic tracheal transplantation can be a model for late stages of obliterative bronchiolitis Orthotopic or heterotopic transplantation is currently the only available option to restore fertility using cryopreserved ovarian tissue. Alternatives such as in vitro follicular culture require additional research before becoming available for humans (Hovatta, 2000; Picton et al., 2008) There are two standard operations for performing heart transplantation—orthotopic, in which the recipient heart is excised and replaced in the correct anatomical position by the donor heart, and heterotopic (the so-called 'piggyback' heart transplant), in which the donor heart is placed in the right chest alongside the recipient organ, and anastomosed in such a way to allow blood to pass through either or both hearts

Orthotopic and heterotopic ovarian tissue transplantation

Between 1986 and 1990 we performed heterotopic liver transplantation (HLT) in 17 patients with chronic liver disease. In spite of theoretical advantages and favorable short-term results, we abandoned HLT because of doubts about the long-term outcome and the improved results of standard orthotopic liver transplantation (OLT) heterotopic transplantation transplantation of tissue typical of one area to a different recipient site. homotopic transplantation orthotopic transplantation. living nonrelated donor transplantation living unrelated donor transplantation Importantly, we found that heterotopic transplantation preserves ovarian follicle integrity to a greater degree (i.e., lower expression of apoptosis markers) than orthotopic transplantation, and cryopreservation does not exacerbate expression of apoptosis's markers The Achilles heel of clinical lung transplantation remains bronchiolitis obliterans, which is defined as fibrotic occlusion of the small airways. Currently, heterotopic tracheal transplantation and graft versus host disease after bone marrow transplantation are models utilized to study airway changes that mimic human chronic rejection 5,18 Autologous orthotopic transplantation of previously frozen cortical tissue has led to a series of live births (Table 5.1) and is currently the most effective technique for transplantation. Heterotopic Ovarian Transplantation Common sites for heterotopic transplantation are subcutaneous tissues such as the forearm and abdomen

Heterotopic transplantation, also called piggyback transplantation, is accomplished by leaving the recipient's heart in place and connecting the donor heart to the right side of the chest. The procedure is rare compared to orthotopic transplantation and is advantageous because the new heart can act as an assist device if complications. A high percentage of patients with ESRD currently are not candidates for a heterotopic kidney transplant because of associated severe vascular pathology, obesity, or retained iliac fossae from a former graft. In such situations, where heterotopic transplant is not appropriate, an orthotopic kidney transplant (OKT) is a good alternative There are two very different surgical approaches to liver transplantation: the orthotopic and the heterotopic approach, both of which can take up to ten hours to complete. Because the length of this surgery is different for every patient, families should talk with the surgeon about what to expect

In the first two cases, we illustrated the robot-assisted orthotopic and heterotopic approaches using Alloderm. Robotic ovarian transplantation may increase precision, provide more delicate graft handling, and reduce the time from tissue thawing to transplantation To perform the orthotopic tracheal transplantation surgical training is necessary and luminal obliteration of the transplanted trachea appears after 60 days instead of 28 days in the heterotopic model (3, 7). Also, maximal luminal obliteration achieved is app. 45% instead of 100% in the heterotopic model (3, 7) There are two primary approaches for autotransplantation of ovarian tissue: heterotopic, in which cortical fragments can be transplanted subcutaneously or to other sites; and orthotopic, in which the fragments are transplanted into their original site (s) or into the remaining ovary near the ovarian fossa or infundibulopelvic ligaments [ 2 ] In the first two cases, we illustrated the robot-assisted orthotopic and heterotopic approaches using Alloderm. Robotic ovarian transplantation may increase precision, provide more delicate graft handling, and reduce the time from tissue thawing to transplantation (6, 8) Heart Transplantation: The Present Status of Orthotopic and Heterotopic Heart Transplantation. by D.K. Cooper, R.P. Lanza | Read Reviews. Paperback. Current price is , Original price is $109.99. You . Buy New $109.99 $ 109.99. Ship This Item — Qualifies for Free Shippin

The Surgical Techniques of Orthotopic and Heterotopic

  1. A heart transplant, or a cardiac transplant, is a surgical transplant procedure performed on patients with end-stage heart failure or severe coronary artery disease when other medical or surgical treatments have failed. As of 2018, the most common procedure is to take a functioning heart, with or without both lungs, from a recently deceased organ donor (brain death is the standard ) and.
  2. al region. FERTILITY PRESERVATION IN CANCER PATIENTS/OCUVANJE FERTILITETA KOD ONKOLOSKIH PACIJENAT
  3. al subcutaneous site, was performed to re store the ovarian function of a 29-year-old woman previously trea ted with bone marrow transplantation (BMT) for Hodgkin's disease. Ovaria
  4. In the heterotopic transplantation, cortical fragments can be grafted subcutaneously at various sites whereas in orthotopic transplantation cortical pieces are transplanted into its original location. Both approaches have their own advantages and disadvantages. While natural pregnancy can occur in orthotopic transplantation, heterotopic.
  5. In 1988, we reported on the favorable short-term results of auxiliary partial liver transplantation in a small number of patients with end-stage chronic liver disease. 1 Originally, this procedure, which will be referred to as heterotopic liver transplantation (HLT), was developed for patients deemed too ill for standard orthotopic liver transplantation (OLT)
  6. g available for humans ( Hovatta, 2000 ; Picton et al ., 2008 )
  7. Two surgical techniques are commonly used for small intestinal transplantation: heterotopic (accessory) intestinal grafting (HIT), where the small bowel is initially defunctioned with restoration of intestinal continuity at a later date, and orthotopic (in continuity) intestinal grafting (OIT), where the small bowel is immediately anastomosed to the native intestine

Heterotopic vs. Orthotopic Liver Transplantation for ..

Video: Orthotopic Transplantation - an overview ScienceDirect

Heterotopic heart transplantation: where do we stand

  1. The book stresses heterotopic transplantation, however, at the expense of reviewing information and outcome on the more commonly practiced technique of orthotopic transplantation. Cyclosporine A is commonly used as the main immunosuppressive agent in most institutions
  2. Five long-term survivors of heart transplantation were reinvestigated. Two patients had undergone orthotopic heart transplantation over 11 and 9 years earlier and constitute two of the world's longest-surviving patients after this procedure. Three patients had undergone heterotopic heart transplantation (one left heart bypass alone and two biventricular bypass) four to six years earlier
  3. About Press Copyright Contact us Creators Advertise Developers Terms Privacy Policy & Safety How YouTube works Test new features Press Copyright Contact us Creators.
  4. Heart Transplantation The Present Status of Orthotopic and Heterotopic Heart Transplantation. Editors: Cooper, D.K., Lanza, R.P. (Eds.) Free Preview. Buy this book eBook 74,89 € price for Spain (gross) Buy eBook ISBN 978-94-011-7324-7; Digitally watermarked, DRM-free.
  5. Heterotopic limb transplantation procedures fulfill these criteria and are easier to perform than orthotopic limb transplants. Mastering rodent microsurgical models requires solid experience in microsurgery and animal care. Herein is reported a reliable and reproducible model of partial heterotopic osteomyocutaneous flap transplantation in rats.

Indeed, orthotopic and heterotopic transplant of the whole ovary the freezing of ovarian tissue may be combined with the with vascular anastomosis of the pedicle vessels was per- removal, via puncture, of small antrum follicles that may be formed successfully in humans with fresh organs in cases present in the ovary at the time of harvesting. 10-14 weeks after transplantation, and later embryo development. Conclusion(s): Since our first report of successful restoration of ovarian function after orthotopic transplantation of frozen-banked ovarian tissue in 2000 (1), followed by our first reports of subcutaneous heterotopic transplantation techniques (2, 3), ovarian tissu Two murine tracheal transplantation methods, heterotopic and orthotopic , have been developed and standardized for the study of the OAD pathophysiologic process, although the role of ventilation has not been previously examined in either model. Initial concerns about the role of ventilation began with the stable duplication of characteristic.

Advantages and Disadvantages of Heterotopic Transplantatio

  1. ipig model Lia Cruz V. C. Damásio1,2*, José Maria Soares-Júnior1, Jairo Iavelberg1, Gustavo A. R. Maciel1, Manuel de Jesus Simões1, Ricardo dos Santos Simões1, Eduardo Vieira da Motta1,2, Maria Cândida Pinheiro Baracat1 and Edmund C. Baracat1,
  2. heterotopic or orthotopic transplantation of fresh or frozen ovarian cortex [17]. Radford performed the first orthotopic reimplantation of ovarian cortical strips [18]. Laparoscopic technique for orthotopic transplantation of the ovary has been reported [19]; however, it was not until 2004 when Donnez [20] reported the firs
  3. A heterotopic heart transplant allows for a donor heart to be piggybacked to a patient's original heart. This merging of the hearts enables the original heart to do its job. This kind of transplant rare and is only performed when the patient is not eligible for an orthotopic heart transplant
  4. Heart Transplantation: The Present Status of Orthotopic and Heterotopic Heart Transplantation (Paperback) Average Rating: ( 0.0 ) stars out of 5 stars Write a review D K Cooper; R P Lanz
  5. There were two early deaths in the heterotopic transplant group and eight in the orthotopic group (p = 0.87). Kaplan-Meier survival analysis of survival was performed. Conclusions Heterotopic heart transplantation is a viable transplant option for selected high-risk heart transplant recipients in spite of somewhat poorer outcomes
  6. Substantial technological advances in mechanical circulatory support have caused a shift in the management of end-stage heart failure. From the 1970s through the 1990s, heterotopic heart transplantation was routinely performed in patients in whom orthotopic transplantation was likely to fail
  7. Recent reports of live births after orthotopic transplantation raised hopes for the future success of this procedure. However, doubts remained whether the reported pregnancies were as a result of resumed function in the remaining ovary. We recently performed an autologous heterotopic ovarian transplantation in a 32-year-old Hodgkin lymphoma.

Heterotopic vs. orthotopic liver transplantation for ..

Heterotopic transplantation definition of heterotopic

Although HHTx has, on average, higher morbidity and mortality rates than does orthotopic transplantation, investigators 3 have suggested that the increased risks associated with receiving heterotopic cardiac allografts can be attributed to the indications for HHTx, such as size mismatch and high TPG, rather than to the procedure itself The heterotopic heart transplant was pioneered by Christian Barnard in the late 1970s as a way to treat acute rejection in the pre-cyclosporine era. The technique was also used for the treatment of severe pulmonary hypertension, in patients unable to have an orthotopic heart transplant. Some surgeons have used the heterotopic heart transplant as a way to increase the donor heart pool around. Orthotopic transplantation of cryopreserved ovarian tissue at ovarian and peritoneal sites, together with a heterotopic transplantation at the abdominal subcutaneous site, was performed to restore the ovarian function of a 29-year-old woman previously treated with bone marrow transplantation (BMT) for Hodgkin's disease

Heterotopic liver transplantation avoids the resection of the host liver and is a useful model to help differentiate between these two possibilities. In this study the fibrinolytic system was evaluated in 10 orthotopic liver transplantations, 18 heterotopic liver transplantations and a control group of 10 partial hepatic resections Auxiliary heterotopic liver transplantation (AHLT) with portal vein arterialization (PVA) has several advantages over auxiliary orthotopic liver transplantation: NL resection is not required, and the hepatic hilum is left untouched; thus, the chances of liver regeneration are optimal The heart transplant programme at Groote Schuur Hospital and the University of Cape Town has continued uninterruptedly since the first human transplant in 1967. Orthotopic heart transplantation was followed by the heterotopic method in 1974, considerably improving the clinical results Orthotopic transplantation is the most common type of liver transplant performed currently and consists of removing the recipient's liver and replacing it with a donor liver.[7] To join the donor liver to the recipient, 4 vascular anastomoses and a biliary anastomosis are created To the Editor: We read with interest the report by Ravaioli et al, and congratulate the authors on achieving a good outcome from their modification of the heterotopic liver transplantation (HLT) procedure. 1 We would like to highlight some aspects of the HLT procedure and the science behind its failure to gain widespread acceptance. Over 3 decades ago, HLT was promoted as a safer way to.

The procedure was successful, and the patient underwent a successful orthotopic heart transplantation six months after being placed on TAH. In the case of rejection and heart dysfunction, rescuing heterotopic heart transplantation (HHT) patients might be challenging because of high panel reactive antibodies (PRA) and availability of donor hearts Define orthotopic transplantation. orthotopic transplantation synonyms, orthotopic transplantation pronunciation, orthotopic transplantation translation, English dictionary definition of orthotopic transplantation. v. trans·plant·ed , trans·plant·ing , trans·plants v. tr. 1. while in heterotopic transplantation the tissue is. Abstract. We compared blood loss and hemostasis in pigs which had undergone either orthotopic liver transplantation (OLT) (group A, n= 12) or auxiliary heterotopic partial liver transplantation (APLT) (group B, n= 11). Blood samples were taken at regular intervals during and after the operations. In both groups, nine animals survived longer than 24 h and data from these animals were used for. A comparison with the International Society for Heart and Lung Transplantation heterotopic heart transplant 4-year actuarial survival (Cutler-Ederer) of 48% (unpublished data, L Edwards, UNOS Registry) is similar to the 51% for our heterotopic heart transplant group, both being significantly inferior to the 76% 4-year survival of our orthotopic. Alexopoulos D, Yusuf S, Bostock J, et al. Ventricular arrhythmias in long term survivors of orthotopic and heterotopic cardiac transplantation. Br Heart J 1988; 59:648. Berke DK, Graham AF, Schroeder JS, Harrison DC. Arrhythmias in the denervated transplanted human heart. Circulation 1973; 48:III112. de Jonge N, Jambroes G, Lahpor JR, Woolley SR

Frontiers | Rat Heterotopic Heart Transplantation Model to

Heterotopic heart transplantation is seldom used but may be due a renaissance. In a left assist configuration, heterotopic heart transplantation could expand the pool of heart donors and also enable transplantation in groups of patients who are currently not eligible for a heart transplant homotopic transplantation: [ trans″plan-ta´shun ] the transfer of living organs or tissue from one part of the body to another or from one individual to another. Transplantation and grafting mean the same thing, although the term grafting is more commonly used to refer to the transfer of skin. In dentistry, transplantation refers to the. Chapter 14 Transoiantalion If both donor kidneys are available, which is preferred Left : longer renal vein allows for easier anastomosis. Should the placement of the kidney be hetero- or orthotopic Heterotopic : retroperitoneal in the right lower quadrant or left lower quadrant above the inguinal ligament. Define anastomoses of a heterotopic kidney transplant 1) Renal artery to iliac artery Auxiliary liver transplantation was originally started in Western countries in the form of heterotopic auxiliary liver transplantation for end-stage liver disease. It thereafter developed into the form of auxiliary partial orthotopic liver transplantation for acute liver failure. In Japan, where living-donor liver transplantation is the main. Heterotopic liver transplantation is a surgical technique designed to solve some of the problems of the conventional orthotopic procedure by avoiding the removal of the patient's own liver. Heterotopic transplantation has never become a viable alternative for orthotopic transplantation, and was abandoned even in Rotterdam after 23 were done in.

Heterotopic ovarian transplantation results in less

One aspect of the advances in surgical techniques is the evolution of the auxiliary heterotopic liver transplantation (HL1). This is an alternative to the orthotopic procedure and has some attractive potential advantages over OLT. Another progress in liver preservation is the extension of the duration of graft preservation Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease The JoVE video player is compatible with HTML5 and Adobe Flash. Older browsers that do not support HTML5 and the H.264 video codec will still use a Flash-based video player

BibTeX @MISC{Bakker_acomparison, author = {C. Minke Bakker and Jan D. Blankensteijn and Peter Schlejen and Robert J. Porte and Maria J. Gomes and Harald I. H. Lampe and Jeanne Stibbe and Onno T. Terpstra}, title = {A Comparison Between Orthotopic and Heterotopic Transplantation in the Pig}, year = {} Methods of Transplantation OHT is a method of allograft transplantation that involves complete to near-complete removal of the recipient's native heart. Heterotopic heart trans-plant is an alternate surgical approach designed to provide left ventricular, or more commonly, biventricular assistance by grafting the native an

Orthotopic Mouse Lung Transplantation as Experimental

Compared with two heterotopic allografts, orthotopic allografts had less occlusion of the tracheal lumen as well as less infiltration of CD4+/CD8+ mononuclear cells and myofibroblasts, but more regenerative epithelium and neovascularized vessels (P<0.05).ConclusionsOrthotopic tracheal transplantation in mice can be considered as a model to. Because of the different etiologies for tricuspid regurgitation, multiple percutaneous transcatheter options for tricuspid valve repair for severe regurgitation are being studied and have been developed, including annuloplasty systems, leaflet and coaptation devices, vena caval (heterotopic) valve implantations, and tricuspid valve (orthotopic. Heterotopic tumors were also associated with a more intense desmoplastic reaction compared with orthotopic tumors, evidenced by thicker surrounding fibrous capsules, and more frequent deposition of collagen fibers throughout the tumor parenchyma (Fig. 5A)

Heart - Transplant Livin

As adjectives the difference between orthotopic and heterotopic. is that orthotopic is (anatomy) in the normal position while heterotopic is (medicine) occurring in an abnormal anatomical location suggested that oocyte quality might be compromised by transplantation to a heterotopic site. Indeed, they only obtained a four-cell embryo from 20 oocytes retrieved from tissue transplanted under the skin of the abdomen. Temperature and pressure changes in the subcutaneous space could damage the oocytes candidates for a heterotopic kidney transplant because of associated severe vascular pathology, obesity, or retained iliac fossae from a former graft. In such situations, where heterotopic transplant is not appropriate, an orthotopic kidney transplant (OKT) is a good alternative. Gil-Vernet et al published the largest series of OKT i

Orthotopic liver transplantation, in which the previous liver is removed and the transplant is placed at that location in the body; Orthotopic heart transplantation; Orthotopic kidney transplantation. When organs are transplanted to a different anatomical location the procedure is said to be heterotopic (e.g. heterotopic heart transplantation) Diagnostic and therapeutic management of hepatic artery thrombosis and stenosis after orthotopic and heterotopic liver transplantation

Until the present time, the first experimental liver transplant which led to the development of human liver transplantation is attributed to C. Stuart Welch who performed a heterotopic transplant in the canine species in 1955. In 1956, Jack Cannon is credited with the first animal orthotopic liver transplant although the species was not disclosed Heterotopic cardiac transplantation first introduced by Bernard in 1974 currently is rarely used as the procedure of choice when orthotopic cardiac transplantation can be considered. Specific indic.. cluding orthotopic lung transplantation in rodents and large animals, orthotopic tracheal transplantation and Heterotopic tracheal transplant models commonly involve a mouse or rat tracheal segment implanted in subcuta-neous tissue or in the omentum (Figure 1C). After trans o new surgical techniques for orthotopic (ORT) and heterotopic (HET) hind limb transplantation. Methods. BALB/c hind limbs were transplanted to BALB/c or C57BL6 recipients using a nonsuture cuff technique. ORT: donor femoral vessels were anastomosed to recipient femoral vessels, the sciatic nerve approximated end-to-end and osteosynthesis was performed using an intramedullary rod. HET/cervical.

Orthotopic Kidney Transplantation: An Alternative Surgical

  1. The first auxiliary liver transplantation in human was performed by Absolon et al. in 1964 in the form of a heterotopic auxiliary liver transplantation (HALT). Since then, more than 50 HALTs have been carried out, but with disappointing results
  2. Orthotopic and Heterotopic Transplantation What, then, is an Orthotopic Liver Transplant? Orthotopic means In the same place. The patient's diseased liver is removed entirely and replaced.
  3. The illustrated techniques include robot-assisted orthotopic (technique 1) and heterotopic (technique 2) approaches utilizing the da Vinci Xi (Intuitive Surgical Inc., CA, USA) robotic system and a decellularized human extracellular tissue matrix (Alloderm; LifeCell Corp., Branchburg, NJ, USA) as a tissue scaffold, as well as a percutaneous.
  4. Successful orthotopic transplantation of ewe cryopreserved ovarian tissue was first performed by Gosden in 1994 (Gosden et al., 1994). The orthotopic transplantation is the site most suitable compared to the heterotopic site, because it is the natural environment, with comfortable temperatures and pressures for proper follicular development
  5. g an important modality of therapy for irre- versible FHF (2,9-101 and has been shown to correct the basic metabolic defect in Wilson' s disease (2,11- 14). Heterotopic liver transplantation (HLT] for fulmi

Liver - Transplant Livin

In this report the history and clinical results of heterotopic liver transplantation (HLT) are reviewed and some special aspects of current research on HLT are highlighted. The first laboratory experiments on liver transplantation were performed with auxiliary heterotopic grafts. The initial clinical results of HLT, however, were disappointing and orthotopic liver transplantation (OLT) evolved. original form as heterotopic auxiliary liver transplantation (HALT) was promoted by some authors as a safer way to perform a LT avoiding the seemingly overwhelming risks of recipient hepatectomy.(1) Over the past 2-3 decades, with improvements in surgical techniques in orthotopic liver transplantation (OLT), the technique o

Robot-assisted orthotopic and heterotopic ovarian tissue

Orthotopic and heterotopic transplantation of the heart: the Cape Town experience. By D. K. Cooper. Abstract. The world's first human-to-human heart transplant was performed at Groote Schuur Hospital on the 2nd December 1967. Between 1967 and 1973, 10 patients underwent orthotopic heart transplantation. Four lived for more than 1 year. The. Multiple animal models of OB exist, including orthotopic lung transplantation in rodents and large animals, orthotopic tracheal transplantation and heterotopic transplantation of a trachea in variable sites such as subcutaneous, intraomental and intrapulmonary sites. The most important issue for researchers is not specifically which model is. Orthotopic heart transplantation (OHT) is a well-established and commonly utilized procedure for patients with end-stage heart failure. Heterotopic heart transplantation (HHT) is a surgical procedure that allows the graft to be connected to the native heart in a parallel fashion to provide a kind of biological biventricular or univentricular. There are 2 ways to perform heart transplant: First and the most convenient way is the orthotopic procedure. In this procedure, the patient's heart is replaced with the donor's heart. Second and the rarely used method is a heterotopic heart transplant, also known as piggyback transplant

Orthotopic Heart Transplantation: Bicaval Versus Biatrial Surgical Technique. By Sofia Martin-Suarez, Marianna Berardi, Daniela Votano, Antonio Loforte, Giuseppe Marinelli, Luciano Potena and Francesco Grigioni. Submitted: November 27th 2017 Reviewed: March 27th 2018 Published: October 10th 2018. DOI: 10.5772/intechopen.7680 Zhao W, Ge X, Sun K, et al. Acute respiratory distress syndrome after orthotopic liver transplantation. J Crit Care. 2016 Feb. 31(1):163-7. . Roberts SK, Kemp W. Salvage therapies for autoimmune. The results of APLT in humans during the initial 2 decades were discouraging. 2 In the 1990s, however, successful auxiliary partial orthotopic liver transplantation (APOLT) cases were documented in hepatic failure 3,4 and metabolic liver disease. 5 Subsequently, several case series were reported. 6-10 Many of these achieved favorable results.

The present study defines the variation in HR over 24 hours after orthotopic and heterotopic cardiac transplantation and compares it with the recipient's own heart-in the case of the heterotopic transplantation-and with normal healthy volunteers. MethodsStudy population: Nineteen transplant recipients who survived >6 months were studied Most reports on heterotopic heart transplantation indicate fewer favorable outcomes than with orthotopic transplantation. But many of the hearts used for heterotopic transplantation have been marginal because of small donor size, prolonged ischemia, and other donor-related problems that led to ejection fractions of <50% Define heterotopic transplantation. heterotopic transplantation synonyms, heterotopic transplantation pronunciation, heterotopic transplantation translation, English dictionary definition of heterotopic transplantation. v. trans·plant·ed , trans·plant·ing , trans·plants v. tr. 1. Related to heterotopic transplantation: orthotopic.

Heterotopic Heart Transplantation | IntechOpen

Fourteen long term survivors with orthotopic (recipient heart replaced by donor heart) and nine with heterotopic cardiac transplants (recipient heart retained) had 24 hour ambulatory electrocardiographic monitoring to detect ventricular arrhythmias. Arrhythmia was uncommon in the patients with orthotopic transplants; none of them had more than one extrasystole per hour Heart transplantation is a relatively infrequent but technically demanding procedure in pediatric cardiac surgery. Orthotopic heart transplantation is often offered to older children or adolescents following multiple previous operations, but with advances in intensive care, diagnostics, and management, more infants with complex congenital heart diseases are being listed for transplantation orthotopic: [ or″tho-top´ik ] 1. occurring at the normal place in the body. 2. pertaining to a tissue transplant grafted into its normal place in the body Orthotopic transplantation of fresh ovarian cortex: a report of two cases. Reprint requests: Professor J. Donnez, Department of Gynecology, Université Catholique de Louvain, Cliniques Universitaires Saint-Luc, Av. Hippocrate, 10 B-1200 Brussels, Belgium (FAX: 32-2-764-95-07)

Pediatric Liver Transplantation | IntechOpenHonoring 50 Years of Clinical Heart Transplantation in

Heterotopic cardiac transplantation first introduced by Bernard in 1974 currently is rarely used as the procedure of choice when orthotopic cardiac transplantation can be considered. Specific indications for heterotopic cardiac transplantation include elevation of pulmonary vascular resistance and availability of a small or poorly functioning donor organ for a mortally ill recipient. Most. Allogeneic transplants rejected their allografts at a mean of 12.8 days (with skin) and 20.6 days (without). Our heterotopic limb transplantation model takes less time and is less stressful to the animals, while allowing for early observation of graft skin rejection, when compared to orthotopic whole-limb transplantation It is a great pleasure for me to contribute a brief introduction to this volume, to which so many of my colleagues at Groote Schuur Hospital and the University of Cape Town Medical School have contributed A heterotopic liver transplantation refers to placement of the donor liver in a different location, typically with the native liver remaining in situ. The overwhelming majority of liver transplantations are orthotopic. Split liver transplantation refers to dividing a donor liver into two grafts that can be used for two recipients Uterine transplantation in the sheep model has been described as a partial or whole orthotopic graft from a living donor with vascular anastomoses. As an alternative to surrogate pregnancy or adoption uterus transplantation might be indicated for cases of infertility of uterine origin. The main complications might be rejection and thrombosis

Heterotopic and Orthotopic Tracheal Transplantation in

Some patients with cirrhosis who are too ill to undergo orthotopic liver transplantation have been treated with heterotopic liver transplantation. However, use of heterotopic liver transplantation for fulminant hepatocellular failure has not been successful. This case study involves a patient in whom a heterotopic liver transplant was. He is currently alive 14 years post-transplantation. AB - Heterotopic heart transplant (HHT) has traditionally been thought of as creating 2 parallel circulations. We present a case of using the donor heart as a biologic left ventricular assist (bio-LVA)

8Surgical Techniques of Heart Transplantation and Heart